Medscape - Obesity management dosing for Alli, Xenical (orlistat), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy .XENICAL is indicated for obesity management including weight loss and weight maintenance when used in conjunction with a reduced-calorie diet. XENICAL.XENICAL (orlistat) is a lipase inhibitor for obesity management that acts by inhibiting the XENICAL is available for oral administration in dark-blue, hard-gelatin .DESCRIPTION. XENICAL (orlistat) is a gastrointestinal lipase inhibitor for obesity management that acts by inhibiting the absorption of dietary fats. Orlistat.Xenical is a medication for chronic weight management. It is for Take one 120 mg tablet three times a day when you eat your main meals (breakfast, lunch.